You swapped your cigarettes for a vape, thinking it’s a safer, cleaner choice. But a startling new study shatters that assumption — even nicotine-free vaping can harm your blood vessels, raising your risk of heart disease and circulation problems.
Sure, traditional cigarettes pack thousands of toxic chemicals, tar, and carcinogens. Vaping cuts out many of those poisons, but the idea that zero-nicotine vapes are totally harmless? That’s now under serious scrutiny.
If you’ve never smoked before, picking up a vape — nicotine or not — could be putting your health on the line. Researchers recently compared the effects of nicotine-free vaping, regular vaping, and even traditional smoking. But before we dive into those shocking findings, let’s get clear on what vaping really is.
What is vaping?
E-cigarettes, or vapes, are battery-powered devices that heat a liquid into a vapor you inhale. Unlike cigarettes that burn tobacco and spew thousands of harmful chemicals, vapes don’t produce smoke or tar — which is why many people think they’re a safer alternative.
What’s in the vape juice?
Vape juice is mostly a mix of propylene glycol and vegetable glycerin — safe to eat, but inhaling them? That’s a different story. When heated, these ingredients break down into harmful byproducts that can irritate your lungs, causing chronic cough, shortness of breath, and lung inflammation.
The tempting flavors
Vaping’s appeal often lies in its delicious flavors — fruity, minty, or dessert-like. But these flavors often contain toxic chemicals, including:
- Diacetyl — linked to “popcorn lung,” a serious lung disease
- Benzaldehyde — a flavoring that irritates the respiratory system
- Heavy metals — lead, nickel, and tin from vape coils can sneak into the vapor
Even without nicotine, inhaling these toxins over time can seriously damage your lungs.
“You’re exposing yourself to all kinds of chemicals we don’t fully understand — and they’re probably not safe,” warns Dr. Michael Blaha of Johns Hopkins Medicine.
Vaping is booming — but at what cost?
Vaping has surged in popularity, especially among youth. In 2021, over 2 million U.S. middle and high school students reported vaping, with more than 80% using flavored e-cigarettes, according to Johns Hopkins.
So, if you thought vaping — nicotine-free or not — was harmless, it’s time to rethink. Your heart and lungs might be paying a heavier price than you realize.

“What worries me most about vaping’s rise is that it’s attracting people—especially young people—who would’ve never touched a cigarette before,” says Dr. Michael Blaha. “Switching from smoking to vaping is one thing. But starting nicotine use with vaping? That’s a whole different story. And once hooked on nicotine, many end up turning to traditional tobacco products later on.”
The Shocking Truth Unveiled
A groundbreaking 2024 study set out to uncover whether the base liquids and flavoring chemicals in vapes cause harm—even without nicotine.
Researchers tested three groups:
- Nicotine-free vapes
- Nicotine-containing vapes
- Traditional cigarettes
The results? All three impaired blood vessel function. This means nicotine isn’t the only villain behind vaping’s health risks.
The study revealed that “vascular function dropped most after inhaling nicotine-containing e-cigarettes, but even nicotine-free vaping had a significant negative effect,” says Dr. Marianna Nabbout, one of the lead researchers.
She warns, “This highlights how smoking and vaping can acutely impact multiple vascular systems in the body. If a single vaping session can affect your blood vessels immediately, imagine the damage chronic use might cause over time.”
If you’ve been vaping under the impression it’s a safe alternative to smoking, this new research is a wake-up call you can’t ignore.
What are your thoughts on vaping? Please let us know what you think and then share this story so others will be aware of the health risks linked with vaping!